News
The following new faculty have joined the department. Check out their web sites:
Dr. Casey Holliday is interested in form and function of the head of vertebrates and is teaching anatomy to medical students.
Dr. Ariel Goldschmidt is interested in forensic pathology and is working with the Medical Examiner's office.
Dr. Robert McAfee is interested in human anatomy and is teaching anatomy to medical students and undergraduates.
The Residency Program has transitioned to new leadership, with Dr. Douglas Miller as the Director of the Pathology Residency Program, and Dr. Shellaine Frazier as the new Associate Director of the program. Congratulations, Doug and Shellaine!
Home
Ask a Pathologist
Education
Clinical Services
Research
Forensic Services
Clinical & Anatomic Pathology
Anatomical Sciences
People
Links
News
Calendars
Giving to the Department
Contact Us
It is with great pleasure that we announce Dr. Sharon Stack and Dr. George Davis have been named Margaret Proctor Mulligan Professors.
M. Sharon Stack is vice chair for research in the Department of Pathology and Anatomical Sciences. Her research focuses on tumor progression and metastasis. She uses two- and three-dimensional in vitro models of tumors combined with analysis of tumor tissues and in vivo models to analyze mechanisms of metastasis.
George E. Davis holds a primary appointment in the Department of Medical Pharmacology and Physiology, and a secondary appointment in Pathology and Anatomical Sciences. Davis’ research examines both breast cancer and cardiovascular disease by studying the development of new blood vessels, or angiogenesis. Davis studies how to control tumor cell migration and invasion at the molecular level.
The bequest of Margaret Proctor Mulligan of more than $6 million to the University of Missouri enhances efforts to treat and cure patients with two of the most prevalent diseases, cardiovascular disease and breast cancer, by funding more than 10 endowed faculty research positions. Margaret Proctor Mulligan, a breast cancer survivor and supporter of MU, made the donation to the MU School of Medicine. No other gift has created as many endowed faculty positions at MU.
The PAS Department was well represented at the 2009 Life Sciences Week poster sessions with nearly 20 posters! For a schedule of events, please see: http://bondlsc.missouri.edu/lifesciencesweek/search/index.php.
Awards:
Congratulations to Rachel Menegaz, a first-year PhD candidate in the Integrative Anatomy program and an MU Life Sciences Fellow! Rachel won one of only five prizes at the annual international meetings of the American Association of Physical Anthropologists. She was awarded the Mildred Trotter Award for best student presentation on skeletal biology and adaptation for her poster entitled Loaded and spaced out: Plasticity and function of the palate in rabbits, with implications for australopith facial form.
Congratulations to Rebecca Burkhalter, first place poster prize for: Burkhalter R, Liu Y, Symowicz J, and Stack MS “Integrin Regulation of β-catenin Signaling in Ovarian Carcinoma”, National Organization for the Professional Advancement of Black Chemists and Chemical Engineers, Midwest Regional Conference, Indianapolis, IN, October 2008.
Work in the laboratories of the department won First, Second, and Third place in the Health Sciences Research Day symposium in the Basic Science (Category I) group, for work in the labs of Drs. C. William Caldwell and Matthew Ravosa.
Dr. Carol Ward received a LSB Leakey Foundation Award to conduct novel 3D analysis of Koobi Fora Hominin anatomy and variation.
Dr. Jessica Weiberg received a Resident Specialty Grant from the American Society of Clinical Pathology
More New Grants:
Gu, Zezong, American Heart Association National Scientist Development Award
(2009-2013).
Ravosa, Matthew J. “Symphyseal Plasticity, Properties and Performance in
Primate and Non-Primate Mammals “ NSF – Physical Anthropology/Integrative
Organismal Systems (2009-2012)
Wang, Michael, "Development of a Universal Cancer Detection Kit by Specific
DNA Methylation Biomarkers", UM Intellectual Property Fast Track Initiative
Grant (2009-2010).
New Publications (July - November, 2009):
Aldridge K, Hill CA, Austin JR, Percival C, Martinez-Abadias N, Neuberger T, Wang Y, Jabs EW, Richtsmeier JT (2009) Brain phenotypes in two FGFR2 mouse models for Apert syndrome. Developmental Dynamics, in press.
Barbolina M.V., Adley B.P., Kelly D.L., Shepard J., Fought A.J., Scholtens D., Penzes P., Shea L.D. and Stack, M.S. (2009) Downregulation of Connective Tissue Growth Factor by Three-Dimensional Matrix Enhances Ovarian Carcinoma Cell Invasion. Int. J. Cancer 125: 816-825.
Barbolina, M.V., Moss, N.M., Westfall, S.D., Liu Y., Burkhalter, R.J., Marga, F., Forgacs, G., Hudson, L.G. and Stack, M.S. (2009) Microenvironmental Regulation of Ovarian Cancer Metastasis, Cancer Treat Res. 149:319-34.
Hammond, A.S., Ning, J., Ward, C.V. & Ravosa, M.J. (2009) Mammalian limb loading and chondral modeling during ontogeny. Anat. Record, in press. (Special Issue – Experimental Approaches to Primate Morphology)
Harms MP, Wang L, Campanella C, Aldridge K, Moffitt AJ, Kuelper J, Ratnanather T, Miller MI, Barch DM, Csernansky JG (2009) Structural abnormalities in gyri of the prefrontal cortex in individuals with schizophrenia and their nonpsychotic siblings. British Journal of Psychiatry, in press.
Hill CA, Sussan TE, Reeves RH, Richtsmeier JT (2009) Complex contributions of Ets2 to craniofacial and thymus phenotypes of trisomic “Down syndrome” mice. American Journal of Medical Genetics Part A 149A: 2158-2165.
Holliday CM, Witmer LM. (2009) The epipterygoid of crocodyliforms and its significance for the evolution of the orbitotemporal region of eusuchians. Journal of Vertebrate Paleontology 29(3):715-733.
Hudson, L.G., Moss, N.M., and Stack, M. S. (2009) Epidermal Growth Factor Receptor Regulation of Matrix Metalloproteinases in Epithelial Ovarian Carcinoma. Future Oncology 5:323-38.
Hudson, L.G., Zeineldin, R., Silberberg, M. and Stack, M.S. (2009) Activated EGF Receptor in Ovarian Cancer; Cancer Treat Res. 149:203-26.
Jašarević, E., Ning, J., Daniel, A.N., Menegaz, R.A., Johnson, J.J., Stack, M.S. & Ravosa, M.J. (2009) Masticatory loading, function and plasticity: A microanatomical analysis of mammalian circumorbital soft-tissue structures. Anat. Record, in press. (Special Issue – Experimental Approaches to Primate Morphology)
Jensen MD, Sheng W, Simonyi A, Johnson GS, Sun AY, and Sun GY (2009) Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes. Neurochemistry Int. 55, 362-368.
Menegaz RA, Sublett SV, Figueroa SD, Hoffman TJ, Ravosa MJ, Aldridge K (2009) Evidence for the influence of diet on cranial form and robusticity. Anatomical Record, in press. (Special Issue – Experimental Approaches to Primate Morphology)
Ravosa, M.J., Ross, C.F., Costley, D.B., Williams, S.H., Herring, S.W., Liu, Z.J., Rafferty, K.L. & Hylander, W.L. (2009) Allometry of masticatory loading parameters in mammals. Anat. Record, in press. (Special Issue – Experimental Approaches to Primate Morphology)
Shi Z and Stack, M.S. (2009) Molecules of Cell Adhesion and Extracellular Matrix Proteolysis in Oral Squamous Cell Carcinoma. Histol. Histopathol., in press Stack MS and Fishman DA, Editors. Cancer Treatment and Research: Ovarian Cancer. Springer, NY, 2009, pp 1-411 (2nd Edition).
Sun GY, Shelat PB, Jensen MD, He Y, Sun AY, Simonyi A. (2009) Phospholipases A2 and inflammatory responses in the central nervous system. Neuromol. Med. in press.
Wang Q, Sun AY, Simonyi A, Miller DK, Smith RE, Luchtefeld RG, Korthuis RJ and Sun GY. (2009) Oral administration of grape polyphenol extract ameliorates cerebral ischemia/reperfusion-induced neuronal damage and behavioral deficits in gerbils: comparison of pre- and post-ischemic administration. J. Nutr. Biochem. 20:369-377.
Wang Q, Sun AY, Pardeike J. Muller RH, Simonyi A, and Sun GY. (2009) Neuroprotective effects of a nanocrystal formulation of sPLA2 inhibitor PX-18 in cerebral ischemia/reperfusion in gerbils. Brain Res; 1285: 188-195.
Ward CV, Mays S, Child S & B Latimer (2009) Lumbar vertebral morphology and isthmic spondylolysis in a British Medieval population. American Journal of Physical Anthropology, in press.
Bennett, LB, Schnabel JL, Kelchen JM, Taylor KH, Guo J, Arther GL, Papageorgio CN, Shi H, Caldwell CW (2009) DNA Hypermethylation Accompanied by Transcriptional Repression in Follicular Lymphoma. Genes, Chromosomes & Cancer 48:828-841.
Glinsky, V.V., Kiriakova, G., Glinskii, O.V., Mossine, V.V., Mawhinney, T.P. Turk, J.R., Glinskii, A.B., Huxley, V.H., Price, J.E., Glinsky, G.V. (2009) Synthetic Galectin-3 Inhibitor Increases Metastatic Cancer Cell Sensitivity to Taxol-Induced Apoptosis In Vitro and In Vivo. Neoplasia, 11: 901-909.
Heimburg-Molinaro, J., Almogren, A., Morey, S., Glinskii, O.V., Roy, R., Wilding, G.E.,
Cheng, R.P., Glinsky, V.V, Rittenhouse-Olson, K. (2009) Development,
Characterization, and Immunotherapeutic Utilization of Peptide Mimics of the
Thomsen-Friedenreich Carbohydrate Antigen. Neoplasia, 11: 780-792.
Holliday, C. M. (2009) New Insights into Dinosaur Jaw Muscle Anatomy. The
Anatomical Record 292:1246-1265.
Anthony DC, Frosch MP, DeGirolami UL. (2009) Peripheral nerve and skeletal
muscle. In: Kumar V, Abbas AK, Fausto N, eds. Robbins and Cotran Pathologic
Basis of Disease, 8th Edition. Philadelphia: Elsevier Saunders, 1257-77.
Barbolina M.V., Adley B.P., Kelly D.L., Shepard J., Fought A.J., Scholtens D., Penzes
P., Shea L.D. and Stack, M.S. (2009) Downregulation of Connective Tissue
Growth Factor by Three-Dimensional Matrix Enhances Ovarian Carcinoma Cell
Invasion. Int. J. Cancer, in press
Frosch MP, Anthony DC, DeGirolami UL. (2009) The central nervous system. In:
Kumar V, Abbas AK, Fausto N, eds. Robbins and Cotran Pathologic Basis of
Disease, 8th Edition. Philadelphia: Elsevier Saunders, 1279-1344.
Glinsky, V.V., Kiriakova, G., Glinskii, O.V., Mossine, V.V., Mawhinney, T.P. Turk, J.R.,
Glinskii, A.B., Huxley, V.H., Price, J.E., Glinsky, G.V. (2009) Synthetic Galectin-3
Inhibitor Increases Metastatic Cancer Cell Sensitivity to Taxol-Induced
Apoptosis In Vitro and In Vivo. Neoplasia, in press.
Heimburg-Molinaro, J., Almogren, A., Morey, S., Glinskii, O.V., Roy, R., Wilding, G.E.,
Cheng, R.P., Glinsky, V.V, (2009) Rittenhouse-Olson, K. Development,
Characterization, and Immunotherapeutic Utilization of Peptide Mimics of the
Thomsen-Friedenreich Carbohydrate Antigen. Neoplasia, in press
Little RR, Rohlfing CL. (2009) HbA1c Standardization: Background, Progress and
Current Issues. Lab Medicine 40:368-373.
Miller, DC (2009) Modern Surgical Neuropathology. Cambridge University
Press. ISBN 978-0-521-86932-4. 536 pages.
Moss, N.M., Wu Y.I., Liu Y, Munshi H.G. and Stack M.S. (2009) Modulation of
the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances
Invasion and Proliferation in Three-Dimensional Collagen Matrices. J. Biol.
Chem., in press.
Moss N.M., Barbolina M.V., Liu Y., Sun L., Munshi H.G., and Stack, M.S. (2009)
Ovarian Carcinoma Cell Detachment and Multi-cellular Aggregate Formation are
Regulated by MT1-MMP: A Potential Role in Intra-Peritoneal Metastatic
Dissemination. Cancer Research, in press.
Ravosa, M.J, Hogg, R.T. & Vinyard, C.J. (2009) Exudativory and primate skull
form. In A. Burrows & L.T. Nash (Eds.): Evolution of Exudativory in Primates.
New York: Springer, in press.
Ravosa, M.J. & Daniel, A.N. (2009) Ontogeny and phyletic size change in living
and fossil lemurs. American Journal of Primatology, in press. (Invited
Symposium Volume – Body Size in Primate
Recent Presentations:
Aldridge, K “Similarities and differences in brain phenotypes in two mouse models for Apert syndrome”. Presented to the Department of Genetics and Genomic Sciences, Mt. Sinai Medical Center, New York, NY, July 2009 .
Daniel, A.N., Ning, J., Stock, S.R., Stack, M.S. & Ravosa, M.J. (2009) “Plasticity of the temporomandibular joint in rabbits.” Summer Conference of Life Sciences Undergraduate Research Opportunity Program (LS UROP) for Undergraduate Science Interns.
Bradley LH, Miller DC, Litofsky NS. “Possible tumor neural stem cell origin for new endothelial cells in glioblastomas.” J Neuropathol Exp Neurol 68, 559, 2009.
Johnson JJ, Shi Z, Frazier S, Jiang R, Stack MS “ Functional Alteration of Oral Squamous Cell Carcinoma Aggressive Behavior Through uPAR-Associated Changes in Gene Expression” Second World Congress of the International Academy of Oral Oncology, Toronto, ON, July 2009.
McGowan P, Wieberg J, Eisenbrey B, Luger A. “Comparison of HLA Crossmatching Methodologies”. College of American Pathologists Annual Meeting, Washington D.C., Oct. 2009
Miller DC, Johannesen EJ, Litofsky NS, Fakhoury FJ. “Angiocentric glioma in the tectal region”. J Neuropathol Exp Neurol 68, 585, 2009.
Miller DC, Muzinich MC, Tacazon MG, Litofsky NS. “Histopathology of an“Unidentified Bright Object” in the brain of an adult patient with Neurofibromatosis Type 1. J Neuropathol Exp Neurol 68, 592-593, 2009.
Wang, M, Nalluri S, Taylor KH, Caldwell CW “Tumor-specific CpG Island Methylation in Protocadherin Family Member PCDH-γ-A12”. American Society of Clinical Pathology 2009 Annual Meeting
Also see the More News >>
To see prior editions of newsletters and awards go to Archived PDF Files >>
Contact Us | Maps and Directions |
Department of Pathology & Anatomical Sciences | School of Medicine | University of Missouri
copyright © The Curators of the University of Missouri | an equal opportunity/ADA institution