Lynda Bennett, Ph.D.
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Research Assistant Professor
phone: 573-884-1742
email: bennettlb@missouri.edu
Biographical sketch
Degrees: BSc, Biological Sciences, University of Exeter, Exeter, Devon, England
PhD, Molecular Genetics, St. Mary’s Hospital Medical School, Imperial College, London, England
Additional study:
Postdoctoral Fellow, Depts of Pediatrics and Internal Medicine and Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas
Research Assistant, Division of Human Genetics, Dept. of Genetics, Washington University School of Medicine, St Louis, MO
Senior Postdoctoral Fellow, Baylor Institute for Immunology Research, Dallas, TX.
Academic appointments:
Assistant Investigator and Director of the Molecular Core, Baylor Institute for Immunology Research, Dallas, TX
Research Assistant Professor, Dept. Pathology and Anatomical Sciences, University of Missouri, Columbia, MO
Interests:
- lupus
- ymphoma
- DNA methylation
- immunopathology
Research description: Dr. Bennett is studying the patterns of DNA methylation in CpG islands of genes in peripheral blood cells from systemic lupus erythematosus patients, and in lymphoid malignancies. Her work includes studying how this process may contribute to dysregulated gene expression observed in lupus and malignancies.
Representative Publications
- Palucka, A.K., Gatlin, J., Blanck, J.P., Melkus, M.W., Clayton, S., Ueno, H., Kraus, E., Cravens, P., Bennett, L., Padgett-Thomas, A., Marches, F., Islas-Ohlmayer, M., Garcia, J.V., and Banchereau, J. (2003). Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors. Blood. 102:3302-10.
- Chomarat P., Dantin P., Bennett L., Banchereau J. and Palucka AK. (2003). TNF skews monocyte differentiation from macrophages to dendritic cells. Journal of Immunology 171:2262-2269.
- Palucka AK., Blanck J-P., Bennett L., Pascual V. and Banchereau J. (2005). Cross-regulation of TNF and IFN-α in autoimmune diseases. PNAS 102 (9):3372-3377.
- Damien Chaussabel, Windy Allman, Ascuncion Mejias, Wendy Chung, Lynda Bennett, Octavio Ramillo, Virginia Pascual, A. Karolina Palucka and Jacques Banchereau (2005). Analysis of significance patterns identifies ubiquitous and disease-specific gene expression signatures in patient peripheral blood leukocytes. Ann. N.Y. Acad. Sci. 1062: 146-154.
- Hongzhen Shi, Tinghua Cao, John E. Connoly, Laurence Monnet, Lynda Bennett, Sylvie Chapel, Claude Bagnis, Patrice Mannoni, Jean Davoust, A. Karolina Palucka and Jacques Banchereau (2006). Hyperthermia enhances CTL cross-priming. Journal of Immunology 176: 2134-2141.
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