Jiankun Cui, MD
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Research Assistant Professor
phone: 573-884-2502
email: cuij@missouri.edu
Biographical sketch
Degrees: MD, Tianjin Medical University, Tianjin, China
Additional study: Laboratory Manager, Microsurgry Specialist, Burnham Institute for Medical Research, La Jolla, CA
Academic appointments: Reserach Assistant Professor of Pathology
Certification:
Interests:
- Development of new in vivo animal models for neurological diseases and in vitro primary cultures of different brain cells for seeking better understanding of neurodegenerative diseases and for translational research applications
Research Description:
Representative Publications
*Helton R, Cui J, Scheel JR, Ellison JA, Ames C, Gibson C, Blouw B, Ouyang L, Dragatsis I, Zeitlin S, Johnson RS, Lipton SA, Barlow C: Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage. J Neurosci. 2005 Apr 20; 25(16): 4099-107.
*Gu Z, Cui J, Brown S, Fridman R, Mobashery S, Strongin AY, Lipton SA: A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia. J Neurosci. 2005 Jul 6; 25 (27): 6401-8.
*Satoh T. Okamoto SI. Cui J. Watanabe Y. Furuta K. Suzuki M. Tohyama K. Lipton SA. Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic phase II inducers. Proc Nat’l Acad Sci USA. 103(3):768-73, 2006.
*Liu CH. Huang S. Cui JK. Kim YR. Fararr C. Moskowitz M. Rosen B. and Liu PK: MR Contrast probes that trace gene transcripts for cerebral ischemia in live animals. MR contrast probes that trace gene transcripts for cerebral ischemia in live animals. FASEB J. 2007 21: 3004-3015
* Li Z, McKercher SR, Cui J, Nie Z, Soussou W, Roberts AJ, Sallmen T, Lipton JH, Talantova M, Okamoto S, and Lipton SA: Myocyte Enhancer Factor 2C as a Neurogenic and Antiapoptotic Transcription Factor in Murine Embryonic Stem Cells. J. Neurosci., Jun 2008; 28: 6557 - 6568
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